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Friday, May 28, 2021

 

Blastulation (Formation of Blastula):

        The process of rearrangement of blastomeres and formation of central fluid filled cavity in the morula is called blastulation.

Site: It occurs in upper part of uterus.

Duration: It is completed after 5 to 6 days of fertilization.

        Morula continuously absorbs the uterine fluid.

        The morula increases in size from 0.15 mm to 0.3 mm in diameter.

        The outer layer of cells becomes flat called trophoblast (Gr. Trophos = to feed) or trophoectoderm.

        It absorbs the uterine fluid and collects between inner mass cells, and trophoblast.

        The space between inner mass cells and trophoblast is called central cavity of blastocoel or blastodermic vesicle.

        The inner mass of megameres shifts to dorsal surface and attaches itself to trophoblast and now looks like a knob at one pole.

        The knob gives rise to the embryo and is called embryonal knob.

        The side of blastocyst to which embryonal knob is attached is known as the embryonic or animal pole, and opposite side as the abembryonic pole/ Vegetal pole.

        The trophoblast does not take part in the formation of the embryo proper.

        It remains external to the embryo and gives rise to the extraembryonic membranes, namely, chorion and amnion.

        The trophoblast cells in contact with the embryonal knob are known as cells of Rauber.

        These cells form only protective and nutritive extra-embryonic membranes.

        As a blastocyst is formed, zona pellucida becomes thinner and finally disappears.

Implantation (Nidation):

        The attachment of blastocyst to the uterine wall is called implantation.

Site: It occurs on the endometrium of the uterus (near the fund us).

Period: It starts about 6-7 days after fertilization. It is continues for 3-4 days and is completed by the 9th or 10th after fertilization. It is under control of hormones.

During implantation:

        i. Zona pellucida dissolves

        ii. The exposed trophoblast or tropho-ectoderm comes in contact with endometrial lining in the region of embryonic pole,

        iii. The trophoblast develops two layers in the region of contact between the blastocysts and endometrium. The outer layer is called syncytiotrophoblast and inner cytotrophoblast.

        iv. Trophoblast cells secrete lytic enzymes, cause breakdown of some endometrial cells, absorb nourishment and divide themselves to form villi

        v. Villi penetrate endometrium for fixation and absorption of nourishment.

        vi. Now the embryo is completely hurried in the endometrium of uterus.

        Once this process of implantation has occurred, the conception is complete and the pregnancy starts. After implantation the syncytiotrophoblast cells secrete human chorionic gonadotropin (HCG) which stimulates corpus luteum to secrete estrogen and progesterone.

        Progesterone suppresses next menstruation.

        By second month, the trophoblast develops into a membrane called chorion which takes over the function of corpus luteum and continues to secrete estrogen and progesterone.

        Progesterone also causes increased secretion of mucus in the cervix of the uterus that forms a protective plug during pregnancy.

(REFER DIAGRAMS FROM TEXTBOOK)



VERY SHORT ANSWER QUESTIONS

1.            What is trophoblast or trophoectoderm?

2.           What are the different terms of blastula cavity?

3.           What are cells of Rauber?

4.           What is blastocyst?

5.           Explain the term embryonic pole?

6.           What is abembryonic pole?

7.           What is the contribution of trophoblast in embryo development?

8.           When does zona pellucida disappear?

9.           What is the rice of blastula?

10.        When blastocyst formation is completed?

11.         What is the source of nourishment for blastula?

12.        What is implantation?

13.        When implantation take place?

14.        Name the layers developed by trophoblast?

15.        How syncytiotrophoblast is produced?

16.        Which type of enzymes is released by syncytiotrophoblast?



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